@article{63e820dfac9049aca0553bc037777645,
title = "Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring AMR bacterial pneumonia",
abstract = "Here we describe the case of a COVID-19 patient who developed recurring ventilator-associated pneumonia caused by Pseudomonas aeruginosa that acquired increasing levels of antimicrobial resistance (AMR) in response to treatment. Metagenomic analysis revealed the AMR genotype, while immunological analysis revealed massive and escalating levels of T-cell activation. These were both SARS-CoV-2 and P. aeruginosa specific, and bystander activated, which may have contributed to this patient's persistent symptoms and radiological changes.",
author = "Michaela Gregorova and Daniel Morse and Tarcisio Brignoli and Joseph Steventon and Fergus Hamilton and Mahableshwar Albur and David Arnold and Matthew Thomas and Alice Halliday and Holly Baum and Christopher Rice and Avison, {Matthew B} and Davidson, {Andrew D} and Marianna Santopaolo and Elizabeth Oliver and Anu Goenka and Adam Finn and Linda Wooldridge and Borko Amulic and Boyton, {Rosemary J} and Altmann, {Daniel M} and Butler, {David K} and Claire McMurray and Joanna Stockton and Sam Nicholls and Charles Cooper and Nicholas Loman and Cox, {Michael J} and Laura Rivino and Massey, {Ruth C}",
note = "{\textcopyright} 2020, Gregorova et al.",
year = "2020",
month = dec,
day = "31",
doi = "10.7554/eLife.63430",
language = "English",
volume = "9",
journal = "eLife",
issn = "2050-084X",
publisher = "eLife Sciences Publications",
}