Preparation of Swellable Hydrogel-Containing Colloidosomes from Aqueous Two-Phase Pickering Emulsion Droplets

Jean Paul Douliez; Nicolas Martin; Thomas Beneyton; Jean Charles Eloi; Jean Paul Chapel; Laurence Navailles; Jean Christophe Baret; Stephen Mann; Laure Béven

doi:10.1002/anie.201802929

Preparation of Swellable Hydrogel-Containing Colloidosomes from Aqueous Two-Phase Pickering Emulsion Droplets

Jean Paul Douliez^*
, Nicolas Martin
, Thomas Beneyton
, Jean Charles Eloi
, Jean Paul Chapel
, Laurence Navailles
, Jean Christophe Baret
, Stephen Mann
, Laure Béven

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

74 Citations (Scopus)

250 Downloads (Pure)

Abstract

The fabrication of stable colloidosomes derived from water-in-water Pickering-like emulsions are described that were produced by addition of fluorescent amine-modified polystyrene latex beads to an aqueous two-phase system consisting of dextran-enriched droplets dispersed in a PEG-enriched continuous phase. Addition of polyacrylic acid followed by carbodiimide-induced crosslinking with dextran produces hydrogelled droplets capable of reversible swelling and selective molecular uptake and exclusion. Colloidosomes produced specifically in all-water systems could offer new opportunities in microencapsulation and the bottom-up construction of synthetic protocells.

Original language	English
Pages (from-to)	7780-7784
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	57
Issue number	26
Early online date	23 Apr 2018
DOIs	https://doi.org/10.1002/anie.201802929
Publication status	Published - 19 Jun 2018

Research Groups and Themes

Bristol BioDesign Institute
Inorganic & Materials

Keywords

aqueous two-phase systems
synthetic biology
encapsulation
sequestration
colloidosomes
water-in-water emulsions

Access to Document

10.1002/anie.201802929

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title = "Preparation of Swellable Hydrogel-Containing Colloidosomes from Aqueous Two-Phase Pickering Emulsion Droplets",

abstract = "The fabrication of stable colloidosomes derived from water-in-water Pickering-like emulsions are described that were produced by addition of fluorescent amine-modified polystyrene latex beads to an aqueous two-phase system consisting of dextran-enriched droplets dispersed in a PEG-enriched continuous phase. Addition of polyacrylic acid followed by carbodiimide-induced crosslinking with dextran produces hydrogelled droplets capable of reversible swelling and selective molecular uptake and exclusion. Colloidosomes produced specifically in all-water systems could offer new opportunities in microencapsulation and the bottom-up construction of synthetic protocells.",

keywords = "aqueous two-phase systems, synthetic biology, encapsulation, sequestration, colloidosomes, water-in-water emulsions",

author = "Douliez, \{Jean Paul\} and Nicolas Martin and Thomas Beneyton and Eloi, \{Jean Charles\} and Chapel, \{Jean Paul\} and Laurence Navailles and Baret, \{Jean Christophe\} and Stephen Mann and Laure B{\'e}ven",

year = "2018",

month = jun,

day = "19",

doi = "10.1002/anie.201802929",

language = "English",

volume = "57",

pages = "7780--7784",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley \& Sons, Ltd.",

number = "26",

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TY - JOUR

T1 - Preparation of Swellable Hydrogel-Containing Colloidosomes from Aqueous Two-Phase Pickering Emulsion Droplets

AU - Douliez, Jean Paul

AU - Martin, Nicolas

AU - Beneyton, Thomas

AU - Eloi, Jean Charles

AU - Chapel, Jean Paul

AU - Navailles, Laurence

AU - Baret, Jean Christophe

AU - Mann, Stephen

AU - Béven, Laure

PY - 2018/6/19

Y1 - 2018/6/19

N2 - The fabrication of stable colloidosomes derived from water-in-water Pickering-like emulsions are described that were produced by addition of fluorescent amine-modified polystyrene latex beads to an aqueous two-phase system consisting of dextran-enriched droplets dispersed in a PEG-enriched continuous phase. Addition of polyacrylic acid followed by carbodiimide-induced crosslinking with dextran produces hydrogelled droplets capable of reversible swelling and selective molecular uptake and exclusion. Colloidosomes produced specifically in all-water systems could offer new opportunities in microencapsulation and the bottom-up construction of synthetic protocells.

AB - The fabrication of stable colloidosomes derived from water-in-water Pickering-like emulsions are described that were produced by addition of fluorescent amine-modified polystyrene latex beads to an aqueous two-phase system consisting of dextran-enriched droplets dispersed in a PEG-enriched continuous phase. Addition of polyacrylic acid followed by carbodiimide-induced crosslinking with dextran produces hydrogelled droplets capable of reversible swelling and selective molecular uptake and exclusion. Colloidosomes produced specifically in all-water systems could offer new opportunities in microencapsulation and the bottom-up construction of synthetic protocells.

KW - aqueous two-phase systems

KW - synthetic biology

KW - encapsulation

KW - sequestration

KW - colloidosomes

KW - water-in-water emulsions

UR - https://www.scopus.com/pages/publications/85048806254

U2 - 10.1002/anie.201802929

DO - 10.1002/anie.201802929

M3 - Article (Academic Journal)

C2 - 29683257

AN - SCOPUS:85048806254

SN - 1433-7851

VL - 57

SP - 7780

EP - 7784

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 26

ER -

Preparation of Swellable Hydrogel-Containing Colloidosomes from Aqueous Two-Phase Pickering Emulsion Droplets

Abstract

Research Groups and Themes

Keywords

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Preparation of Swellable Hydrogel-Containing Colloidosomes from Aqueous Two-Phase Pickering Emulsion Droplets

Abstract

Research Groups and Themes

Keywords

Access to Document

Handle.net

Other files and links

Fingerprint

Equipment

Wolfson Bioimaging Facility

Cite this