Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019

David J Roberts, Grahame S Davis, Michelle J Cole, Dixita Naik, Hitiksha Maru, Neil Woodford, Peter Muir, Paddy Horner, Ian Simms, George Thickett, Paul Crook, Kirsty Foster, Nick Andrews, John Saunders, Helen Fifer, Kate Folkard, O Noel Gill, On Behalf Of The Incident Management Team

Research output: Contribution to journalArticle (Academic Journal)peer-review

4 Citations (Scopus)
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Abstract

We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%.

Original languageEnglish
Number of pages5
JournalEurosurveillance
Volume24
Issue number38
DOIs
Publication statusPublished - 19 Sep 2019

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