Abstract
Objectives
To evaluate the prevalence of smoking in the UK elective cardiac surgery population and its impact on postoperative outcomes.
Design
A retrospective observational cohort study.
Setting
Multicenter study using UK registry data from adults undergoing cardiac surgery.
Participants
People who underwent elective coronary artery bypass grafting, valve surgery, or surgery to the thoracic aorta between 2012 and 2022.
Interventions
Documented smoking status at the time of surgery.
Measurements and main results
Of 170,532 included patients, 7.7% were current smokers, 48.4% former smokers and 43.9% non-smokers. The prevalence of smoking did not change between 2012 and 2022. Current smokers present for surgery at a younger age. Despite a higher burden of comorbidities, smokers were not at increased risk of in-hospital mortality compared to former smokers or non-smokers. However, compared with non-smoking, smoking was associated with a higher risk of deep sternal wound infection (odds ratio [OR] 1.53; p < 0.01) and need for surgical debridement (OR 1.89; p < 0.01). Smokers were also more likely than non-smokers to require renal replacement therapy after aortic arch surgery (OR 1.37; p = 0.049). There was no difference in the incidence of other complications between smokers and non-smokers. The mean length of hospital stay was shorter in smokers than non-smokers (9.1 v 9.2 days; hazard ratio 0.97; p < 0.01).
Conclusions
Smoking was less common in the UK elective cardiac surgery population than in other surgical cohorts within the study period. Smokers presented for surgery at a younger age, were more comorbid and had a higher risk of serious wound infections.
| Original language | English |
|---|---|
| Journal | Journal of Cardiothoracic and Vascular Anesthesia |
| Early online date | 4 Sept 2025 |
| DOIs | |
| Publication status | E-pub ahead of print - 4 Sept 2025 |
Bibliographical note
Publisher Copyright:© 2025 The Authors. Published by Elsevier Inc.
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