Primary cardiac malignant peripheral nerve sheath tumour in a dog

Joshua J. Hardwick; Lou J. Dawson; Stephen D. Cahalan; Emi N. Barker

doi:10.1002/vrc2.547

Primary cardiac malignant peripheral nerve sheath tumour in a dog

Joshua J. Hardwick^*, Lou J. Dawson, Stephen D. Cahalan, Emi N. Barker

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Abstract

A 6-year-old, female labrador retriever was presented for acute onset abdominal distention. Clinical examination identified tachycardia, a novel grade 3/6 right basilar systolic cardiac murmur, a distended abdomen and ventral pitting oedema. Jugular pulses were not present. Echocardiography revealed an infiltrative, intramural cardiac mass, with partial occlusion of the right atrium and ventricle, resulting in isolated caudal vena cava syndrome. Postmortem examination revealed a large mass arising from the base of the right atrium and extending into the ventricular lumen. Histopathological and immunohistochemical findings were consistent with a diagnosis of malignant peripheral nerve sheath tumour, a rare primary cardiac neoplasm in dogs.

Original language	English
Article number	e547
Number of pages	6
Journal	Veterinary Record Case Reports
Volume	11
Issue number	1
Early online date	8 Dec 2022
DOIs	https://doi.org/10.1002/vrc2.547
Publication status	Published - 6 Feb 2023

Bibliographical note

Funding Information:
The study was funded by University of Bristol and Langford Vets internal resources.

Publisher Copyright:
© 2022 The Authors. Veterinary Record Case Reports published by John Wiley & Sons Ltd on behalf of British Veterinary Association.

Keywords

ascites
heart failure
oedema
spindle cell

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title = "Primary cardiac malignant peripheral nerve sheath tumour in a dog",

abstract = "A 6-year-old, female labrador retriever was presented for acute onset abdominal distention. Clinical examination identified tachycardia, a novel grade 3/6 right basilar systolic cardiac murmur, a distended abdomen and ventral pitting oedema. Jugular pulses were not present. Echocardiography revealed an infiltrative, intramural cardiac mass, with partial occlusion of the right atrium and ventricle, resulting in isolated caudal vena cava syndrome. Postmortem examination revealed a large mass arising from the base of the right atrium and extending into the ventricular lumen. Histopathological and immunohistochemical findings were consistent with a diagnosis of malignant peripheral nerve sheath tumour, a rare primary cardiac neoplasm in dogs.",

keywords = "ascites, heart failure, oedema, spindle cell",

author = "Hardwick, {Joshua J.} and Dawson, {Lou J.} and Cahalan, {Stephen D.} and Barker, {Emi N.}",

note = "Funding Information: The study was funded by University of Bristol and Langford Vets internal resources. Publisher Copyright: {\textcopyright} 2022 The Authors. Veterinary Record Case Reports published by John Wiley & Sons Ltd on behalf of British Veterinary Association.",

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doi = "10.1002/vrc2.547",

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T1 - Primary cardiac malignant peripheral nerve sheath tumour in a dog

AU - Hardwick, Joshua J.

AU - Dawson, Lou J.

AU - Cahalan, Stephen D.

AU - Barker, Emi N.

N1 - Funding Information: The study was funded by University of Bristol and Langford Vets internal resources. Publisher Copyright: © 2022 The Authors. Veterinary Record Case Reports published by John Wiley & Sons Ltd on behalf of British Veterinary Association.

PY - 2023/2/6

Y1 - 2023/2/6

N2 - A 6-year-old, female labrador retriever was presented for acute onset abdominal distention. Clinical examination identified tachycardia, a novel grade 3/6 right basilar systolic cardiac murmur, a distended abdomen and ventral pitting oedema. Jugular pulses were not present. Echocardiography revealed an infiltrative, intramural cardiac mass, with partial occlusion of the right atrium and ventricle, resulting in isolated caudal vena cava syndrome. Postmortem examination revealed a large mass arising from the base of the right atrium and extending into the ventricular lumen. Histopathological and immunohistochemical findings were consistent with a diagnosis of malignant peripheral nerve sheath tumour, a rare primary cardiac neoplasm in dogs.

AB - A 6-year-old, female labrador retriever was presented for acute onset abdominal distention. Clinical examination identified tachycardia, a novel grade 3/6 right basilar systolic cardiac murmur, a distended abdomen and ventral pitting oedema. Jugular pulses were not present. Echocardiography revealed an infiltrative, intramural cardiac mass, with partial occlusion of the right atrium and ventricle, resulting in isolated caudal vena cava syndrome. Postmortem examination revealed a large mass arising from the base of the right atrium and extending into the ventricular lumen. Histopathological and immunohistochemical findings were consistent with a diagnosis of malignant peripheral nerve sheath tumour, a rare primary cardiac neoplasm in dogs.

KW - ascites

KW - heart failure

KW - oedema

KW - spindle cell

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DO - 10.1002/vrc2.547

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JO - Veterinary Record Case Reports

JF - Veterinary Record Case Reports

IS - 1

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ER -

Primary cardiac malignant peripheral nerve sheath tumour in a dog

Abstract

Bibliographical note

Keywords

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