Primary immune-mediated thrombocytopenia in a cat

S Tasker, AJ Mackin, MJ Day

Research output: Contribution to journalArticle (Academic Journal)peer-review

11 Citations (Scopus)

Abstract

A young female Somali cat was referred for investigation of chronic intermittent haematuria. Petechiae were found on the ears and ventral abdomen and further investigation revealed severe thrombocytopenia and megakaryocyte hyperplasia. Direct marrow immunohistochemistry detected anti-megakaryocyte autoantibody (Immunoglobulin G), but extensive investigation failed to find secondary causes of immune-mediated thrombocytopenia, so a diagnosis of primary (autoimmune) immune-mediated thrombocytopenia was concluded. Thrombocytopenia persisted despite aggressive immunosuppressive therapy (prednisolone, azathioprine and vincristine) but resolved after oral prednisolone was replaced with dexamethasone.
Translated title of the contributionPrimary immune-mediated thrombocytopenia in a cat
Original languageEnglish
Pages (from-to)127 - 131
JournalJournal of Small Animal Practice
Volume40
DOIs
Publication statusPublished - Mar 1999

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