Abstract
The production of a monoclonal antibody which detects the low-incidence red cell antigen Wra is described. The antibody (BGU1-WR) was isolated following immunization of BALB/tk mice with Wr(a+) cells. BGU1-WR is an IgG1 antibody and reacted in a manner similar to human polyclonal anti-Wra with untreated, protease treated and chemically modified Wr(a+) cells.
Original language | English |
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Pages (from-to) | 222-5 |
Number of pages | 4 |
Journal | Vox sanguinis |
Volume | 67 |
Issue number | 2 |
Publication status | Published - 1994 |
Keywords
- Animals
- Antibodies, Monoclonal
- Erythrocytes
- Female
- Hemagglutination Tests
- Humans
- Incidence
- Isoantigens
- Mice
- Mice, Inbred BALB C
- Species Specificity