Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint files. This application note provides a brief description of the profile–profile algorithm used by PRC.
|Translated title of the contribution||Profile Comparer: a program for scoring and aligning profile hidden Markov models|
|Publication status||Published - 2008|