Prophylactic Antiepileptic Treatment in Tuberous Sclerosis

Prerna Choudhury, Robert Spaull, Sam Amin, Andrew A Mallick, Jayesh S Patel, Finbar O'Callaghan, Andrew L Lux*

*Corresponding author for this work

Research output: Contribution to journalLetter (Academic Journal)peer-review


Jóźwiak et al. suggest that their study, “…provides evidence that preventive antiepileptic treatment in infants with tuberous sclerosis complex improves long-term epilepsy control and cognitive outcome at school age.” The study is problematic, however, because it compares two groups that have been ascertained in entirely different ways: the “Standard” group after presentation with tuberous sclerosis complex and usually epilepsy and the “Preventive” group with suspected or proven tuberous sclerosis complex but without epilepsy.
Original languageEnglish
Pages (from-to)100-101
Number of pages2
JournalPediatric Neurology
Early online date5 Apr 2020
Publication statusPublished - 1 Sep 2020

Bibliographical note

Acceptance date is provisional and based on date of publication.


  • tuberous sclerosis complex
  • vigabatrin
  • antiepileptic drug treatment

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