Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product

T Matsumoto; S Hess; H Kajiyama; T Sakairi; MA Saleem; PW Mathieson; Y Nojima; JB Kopp

doi:10.1152/ajprenal.00597.2009

Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product

T Matsumoto, S Hess, H Kajiyama, T Sakairi, MA Saleem, PW Mathieson, Y Nojima, JB Kopp

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

The podocyte secretory proteome may influence the phenotype of adjacent podocytes, endothelial cells, parietal epithelial cells, and tubular epithelial cells but has not been systematically characterized. We have initiated studies to characterize this proteome, with the goal of further understanding the podocyte cell biology. We cultured differentiated conditionally immortalized human podocytes and subjected the proteins in conditioned medium to mass spectrometry. At a false discovery rate of

Translated title of the contribution	Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product
Original language	English
Pages (from-to)	F776 - F784
Number of pages	9
Journal	AJP - Renal Physiology
Volume	299(4)
DOIs	https://doi.org/10.1152/ajprenal.00597.2009
Publication status	Published - Oct 2010

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CELLULAR BASIS OF ALBUMINURIA
Mathieson, P. W. (Principal Investigator)
1/11/08 → 1/05/12
Project: Research

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title = "Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product",

abstract = "The podocyte secretory proteome may influence the phenotype of adjacent podocytes, endothelial cells, parietal epithelial cells, and tubular epithelial cells but has not been systematically characterized. We have initiated studies to characterize this proteome, with the goal of further understanding the podocyte cell biology. We cultured differentiated conditionally immortalized human podocytes and subjected the proteins in conditioned medium to mass spectrometry. At a false discovery rate of ",

author = "T Matsumoto and S Hess and H Kajiyama and T Sakairi and MA Saleem and PW Mathieson and Y Nojima and JB Kopp",

year = "2010",

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doi = "10.1152/ajprenal.00597.2009",

language = "English",

volume = "299(4)",

pages = "F776 -- F784",

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T1 - Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product

AU - Matsumoto, T

AU - Hess, S

AU - Kajiyama, H

AU - Sakairi, T

AU - Saleem, MA

AU - Mathieson, PW

AU - Nojima, Y

AU - Kopp, JB

PY - 2010/10

Y1 - 2010/10

N2 - The podocyte secretory proteome may influence the phenotype of adjacent podocytes, endothelial cells, parietal epithelial cells, and tubular epithelial cells but has not been systematically characterized. We have initiated studies to characterize this proteome, with the goal of further understanding the podocyte cell biology. We cultured differentiated conditionally immortalized human podocytes and subjected the proteins in conditioned medium to mass spectrometry. At a false discovery rate of

AB - The podocyte secretory proteome may influence the phenotype of adjacent podocytes, endothelial cells, parietal epithelial cells, and tubular epithelial cells but has not been systematically characterized. We have initiated studies to characterize this proteome, with the goal of further understanding the podocyte cell biology. We cultured differentiated conditionally immortalized human podocytes and subjected the proteins in conditioned medium to mass spectrometry. At a false discovery rate of

U2 - 10.1152/ajprenal.00597.2009

DO - 10.1152/ajprenal.00597.2009

M3 - Article (Academic Journal)

C2 - 20630940

SN - 1522-1466

VL - 299(4)

SP - F776 - F784

JO - AJP - Renal Physiology

JF - AJP - Renal Physiology

ER -

Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product

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