Pure-shift IMPRESS EXSIDE: Easy measurement of 1H-13C scalar coupling constants with increased sensitivity and resolution

Ikenna E Ndukwe; Craig P Butts

doi:10.1039/C5RA24926K

Pure-shift IMPRESS EXSIDE: Easy measurement of ¹H-¹³C scalar coupling constants with increased sensitivity and resolution

Ikenna E Ndukwe, Craig P Butts^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

6 Citations (Scopus)

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Abstract

The easy-to-interpret and rapid SelEXSIDE NMR experiment for measuring long-range ¹H–¹³C scalar coupling constants ⁿJ_CHis improved with increased sensitivity and resolution by the incorporation of ‘pure-shift’ homonuclear decoupling and IMPRESS-Hadamard encoding, with typical increases in signal-to-noise of over 300% and 400% demonstrated for small molecule examples, and narrower linewidths enabling measurement of smaller coupling constants.

Original language	English
Pages (from-to)	107192–107199
Number of pages	8
Journal	RSC Advances
Volume	5
Issue number	130
Early online date	7 Dec 2015
DOIs	https://doi.org/10.1039/C5RA24926K
Publication status	Published - 31 Dec 2015

Research Groups and Themes

Organic & Biological

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10.1039/C5RA24926K

RA COM 11 2015 024926 ImpEXSIDE Templated Manuscript
© The Royal Society of Chemistry 2015
Accepted author manuscript, 814 KB

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title = "Pure-shift IMPRESS EXSIDE: Easy measurement of 1H-13C scalar coupling constants with increased sensitivity and resolution",

abstract = "The easy-to-interpret and rapid SelEXSIDE NMR experiment for measuring long-range 1H–13C scalar coupling constants nJCH is improved with increased sensitivity and resolution by the incorporation of {\textquoteleft}pure-shift{\textquoteright} homonuclear decoupling and IMPRESS-Hadamard encoding, with typical increases in signal-to-noise of over 300\% and 400\% demonstrated for small molecule examples, and narrower linewidths enabling measurement of smaller coupling constants.",

author = "Ndukwe, \{Ikenna E\} and Butts, \{Craig P\}",

year = "2015",

month = dec,

day = "31",

doi = "10.1039/C5RA24926K",

language = "English",

volume = "5",

pages = "107192–107199",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "130",

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TY - JOUR

T1 - Pure-shift IMPRESS EXSIDE

T2 - Easy measurement of 1H-13C scalar coupling constants with increased sensitivity and resolution

AU - Ndukwe, Ikenna E

AU - Butts, Craig P

PY - 2015/12/31

Y1 - 2015/12/31

N2 - The easy-to-interpret and rapid SelEXSIDE NMR experiment for measuring long-range 1H–13C scalar coupling constants nJCH is improved with increased sensitivity and resolution by the incorporation of ‘pure-shift’ homonuclear decoupling and IMPRESS-Hadamard encoding, with typical increases in signal-to-noise of over 300% and 400% demonstrated for small molecule examples, and narrower linewidths enabling measurement of smaller coupling constants.

AB - The easy-to-interpret and rapid SelEXSIDE NMR experiment for measuring long-range 1H–13C scalar coupling constants nJCH is improved with increased sensitivity and resolution by the incorporation of ‘pure-shift’ homonuclear decoupling and IMPRESS-Hadamard encoding, with typical increases in signal-to-noise of over 300% and 400% demonstrated for small molecule examples, and narrower linewidths enabling measurement of smaller coupling constants.

UR - https://www.scopus.com/pages/publications/84952360586

U2 - 10.1039/C5RA24926K

DO - 10.1039/C5RA24926K

M3 - Article (Academic Journal)

AN - SCOPUS:84952360586

SN - 2046-2069

VL - 5

SP - 107192

EP - 107199

JO - RSC Advances

JF - RSC Advances

IS - 130

ER -

Pure-shift IMPRESS EXSIDE: Easy measurement of ¹H-¹³C scalar coupling constants with increased sensitivity and resolution

Abstract

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A 13C NMR Coldprobe to Underpin Chemistry Research.

HIGH-FIELD NMR SPECTROSCOPY FOR BIOMOLECULAR RESEARCH

Cite this

Pure-shift IMPRESS EXSIDE: Easy measurement of 1H-13C scalar coupling constants with increased sensitivity and resolution

Abstract

Research Groups and Themes

Access to Document

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Projects

A 13C NMR Coldprobe to Underpin Chemistry Research.

HIGH-FIELD NMR SPECTROSCOPY FOR BIOMOLECULAR RESEARCH

Cite this

Pure-shift IMPRESS EXSIDE: Easy measurement of ¹H-¹³C scalar coupling constants with increased sensitivity and resolution