Radical Diazidation of Alkenes: Cu/Fe/Mn Catalysis and Electrochemical Support

Nisar Ahmed*, Saira Khatoon, Bahar Shirinfar

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

Abstract

The synthetic routes for C-N3 bond formation through a radical mechanism with the use of transition metals provide efficient diazide products, which can be further applied in many transformations to synthesize various valuable nitrogen-containing compounds of pharmaceutical interest. The reported methods evidence stoichiometric heavy metals and toxic reagents (as N3-source) and generally exhibit a limited substrate scope. However, the electrochemical diazidations are found to be environmentally friendly and very simple, while also providing a highly efficient way to synthesize 1,2-diazide derivatives. Moreover, they provide a smart alternative for easy access to 1,2-diamines, which can be used for future modern syntheses.

Original languageEnglish
Pages (from-to)1245-1248
Number of pages4
JournalChemElectroChem
Volume5
Issue number9
Early online date7 Mar 2018
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • Diazidation
  • electrosynthesis
  • terminal alkenes
  • transition metals
  • vicinal amines

Fingerprint Dive into the research topics of 'Radical Diazidation of Alkenes: Cu/Fe/Mn Catalysis and Electrochemical Support'. Together they form a unique fingerprint.

  • Cite this