Rate of adaptation of large populations

F Yu, A Etheridge

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

7 Citations (Scopus)


We consider the accumulation of beneficial and deleterious mutations in asexual populations. The rate of adaptation is affected by the total mutation rate, proportion of beneficial mutations, and population size N. We describe two models: a strong selection model for large population size and a weak selection model for moderate population size. For the strong selection model, we give an argument to show that regardless of mutation rates, as long as the proportion of beneficial mutations is strictly positive, the adaptation rate is at least O(log1−δ N), if the population size is sufficiently large. For the weak selection model, we use a Girsanov transform to perform some preliminary calculations that shed new light on the adaptation rate.
Translated title of the contributionRate of adaptation of large populations
Original languageEnglish
Title of host publicationEvolutionary Biology from Concept to Application
EditorsPierre Pontarotti
Pages3 - 27
Number of pages25
ISBN (Print)9783540789925
Publication statusPublished - 2008


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