RE coil: an antimicrobial peptide regulator

MG Ryadnov, GV Mukamolova, AS Hawrani, J Spencer, R Platt

Research output: Contribution to journalArticle (Academic Journal)peer-review

13 Citations (Scopus)

Abstract

Peptides that make bacteria RE coil: A peptide system designed to regulate antimicrobial intervention switches between antimicrobial and inactive forms. The regulator comprises two α-helical sequences. One of them, R coil, binds to microbial membranes and acts as an antimicrobial component, and is inactivated by the other, E coil, a membrane-inactive peptide (see picture).
Translated title of the contributionRE coil: an antimicrobial peptide regulator
Original languageEnglish
Pages (from-to)9676 - 9679
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number51
DOIs
Publication statusPublished - 14 Dec 2009

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