Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis

Adam D. Daniels, Ivan Campeotto, Marc W. van der Kamp, Amanda H. Bolt, Chi H. Trinh, Simon E. V. Phillips, Arwen R. Pearson, Adam Nelson, Adrian J. Mulholland^*, Alan Berry

^*Corresponding author for this work

School of Chemistry
Biological and Archaeological Chemistry
Computational and Theoretical Chemistry
Infection and Immunity

Research output: Contribution to journal › Article (Academic Journal) › peer-review

38 Citations (Scopus)

2 results

Finished
CCP-BioSim: Biomolecular simulation at the life sciences interface
Mulholland, A. J.
1/10/11 → 1/10/15
Project: Research
COMPUTATIONAL BIOCHEMISTRY: PREDICTIVE MODELLING FOR BIOLOGY AND MEDICINE
Mulholland, A. J.
1/10/08 → 1/04/14
Project: Research

Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis

Projects

Search results

CCP-BioSim: Biomolecular simulation at the life sciences interface

COMPUTATIONAL BIOCHEMISTRY: PREDICTIVE MODELLING FOR BIOLOGY AND MEDICINE