Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes

Valeria V Alvino; Anita C Thomas; Mohamed Ghorbel; Filippo Rapetto; Srinivas Narayan; Michael Kilcooley; Dominga Iacobazzi; Michele Carrabba; Marco Fagnano; William R Cathery; Elisa Avolio; Massimo Caputo; Paolo R Madeddu

doi:10.3389/fbioe.2021.715717

Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes

Valeria V Alvino, Anita C Thomas, Mohamed Ghorbel, Filippo Rapetto, Srinivas Narayan, Michael Kilcooley, Dominga Iacobazzi, Michele Carrabba, Marco Fagnano, William R Cathery, Elisa Avolio, Massimo Caputo^*, Paolo R Madeddu^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

5 Citations (Scopus)

149 Downloads (Pure)

Original language	English
Article number	715717
Number of pages	15
Journal	Frontiers in Bioengineering and Biotechnology
Volume	9
DOIs	https://doi.org/10.3389/fbioe.2021.715717
Publication status	Published - 9 Sept 2021

Bibliographical note

Funding Information:
Hannah Martin, Laboratory Assistant at the University of Bristol is acknowledged for technical assistance.

Funding Information:
This study was supported by the grants from the Sir Jules Thorn Charitable Trust (MCap, and PM), the Enid Linder Foundation (MCap and MRG), the British Heart Foundation (PM), the National Institute for Health Research (NIHR) Bristol Biomedical Research Centre in Cardiovascular Medicine (MCap, PM), and the Medical Research Council with the grant number MR/N027086/1 and entitled “In vitro and in vivo preclinical testing of pericyte-engineered grafts for correction of congenital heart defects” (PM, MCap, and MG).

Publisher Copyright:
© Copyright © 2021 Alvino, Thomas, Ghorbel, Rapetto, Narayan, Kilcooley, Iacobazzi, Carrabba, Fagnano, Cathery, Avolio, Caputo and Madeddu.

Keywords

pericytes
grafts
congenital heart disease
pulmonary artery
tissue engineering

Access to Document

10.3389/fbioe.2021.715717

Full-text PDF (final published version)
This is the final published version of the article (version of record). It first appeared online via Frontiers Media at https://www.frontiersin.org/articles/10.3389/fbioe.2021.715717/abstract . Please refer to any applicable terms of use of the publisher.
Final published version, 3.83 MBLicence: CC BY

Handle.net

Persistent link

Cite this

Alvino, V. V., Thomas, A. C., Ghorbel, M., Rapetto, F., Narayan, S., Kilcooley, M., Iacobazzi, D., Carrabba, M., Fagnano, M., Cathery, W. R., Avolio, E., Caputo, M., & Madeddu, P. R. (2021). Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes. Frontiers in Bioengineering and Biotechnology, 9, Article 715717. https://doi.org/10.3389/fbioe.2021.715717

@article{8fc2c5e6212643678606085c97fb38f1,

title = "Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes",

keywords = "pericytes, grafts, congenital heart disease, pulmonary artery, tissue engineering",

author = "Alvino, {Valeria V} and Thomas, {Anita C} and Mohamed Ghorbel and Filippo Rapetto and Srinivas Narayan and Michael Kilcooley and Dominga Iacobazzi and Michele Carrabba and Marco Fagnano and Cathery, {William R} and Elisa Avolio and Massimo Caputo and Madeddu, {Paolo R}",

note = "Funding Information: Hannah Martin, Laboratory Assistant at the University of Bristol is acknowledged for technical assistance. Funding Information: This study was supported by the grants from the Sir Jules Thorn Charitable Trust (MCap, and PM), the Enid Linder Foundation (MCap and MRG), the British Heart Foundation (PM), the National Institute for Health Research (NIHR) Bristol Biomedical Research Centre in Cardiovascular Medicine (MCap, PM), and the Medical Research Council with the grant number MR/N027086/1 and entitled “In vitro and in vivo preclinical testing of pericyte-engineered grafts for correction of congenital heart defects” (PM, MCap, and MG). Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2021 Alvino, Thomas, Ghorbel, Rapetto, Narayan, Kilcooley, Iacobazzi, Carrabba, Fagnano, Cathery, Avolio, Caputo and Madeddu.",

year = "2021",

month = sep,

day = "9",

doi = "10.3389/fbioe.2021.715717",

language = "English",

volume = "9",

journal = "Frontiers in Bioengineering and Biotechnology",

issn = "2296-4185",

publisher = "Frontiers Media S.A.",

}

Alvino, VV, Thomas, AC, Ghorbel, M , Rapetto, F, Narayan, S, Kilcooley, M, Iacobazzi, D, Carrabba, M, Fagnano, M, Cathery, WR, Avolio, E , Caputo, M & Madeddu, PR 2021, 'Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes', Frontiers in Bioengineering and Biotechnology, vol. 9, 715717. https://doi.org/10.3389/fbioe.2021.715717

TY - JOUR

T1 - Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes

AU - Alvino, Valeria V

AU - Thomas, Anita C

AU - Ghorbel, Mohamed

AU - Rapetto, Filippo

AU - Narayan, Srinivas

AU - Kilcooley, Michael

AU - Iacobazzi, Dominga

AU - Carrabba, Michele

AU - Fagnano, Marco

AU - Cathery, William R

AU - Avolio, Elisa

AU - Caputo, Massimo

AU - Madeddu, Paolo R

N1 - Funding Information: Hannah Martin, Laboratory Assistant at the University of Bristol is acknowledged for technical assistance. Funding Information: This study was supported by the grants from the Sir Jules Thorn Charitable Trust (MCap, and PM), the Enid Linder Foundation (MCap and MRG), the British Heart Foundation (PM), the National Institute for Health Research (NIHR) Bristol Biomedical Research Centre in Cardiovascular Medicine (MCap, PM), and the Medical Research Council with the grant number MR/N027086/1 and entitled “In vitro and in vivo preclinical testing of pericyte-engineered grafts for correction of congenital heart defects” (PM, MCap, and MG). Publisher Copyright: © Copyright © 2021 Alvino, Thomas, Ghorbel, Rapetto, Narayan, Kilcooley, Iacobazzi, Carrabba, Fagnano, Cathery, Avolio, Caputo and Madeddu.

PY - 2021/9/9

Y1 - 2021/9/9

KW - pericytes

KW - grafts

KW - congenital heart disease

KW - pulmonary artery

KW - tissue engineering

U2 - 10.3389/fbioe.2021.715717

DO - 10.3389/fbioe.2021.715717

M3 - Article (Academic Journal)

C2 - 34568300

SN - 2296-4185

VL - 9

JO - Frontiers in Bioengineering and Biotechnology

JF - Frontiers in Bioengineering and Biotechnology

M1 - 715717

ER -