Abstract
Background/ Objective: Some studies from high-income countries suggest that overweight/obesity in children is negatively associated with health-related quality of life (HRQoL). However, the relationship between weight status and HRQoL is not well-established in China and obesity trends follow a different pattern compared with high-income countries. The risk of obesity is greater in children from higher socio-economic backgrounds and higher in boys compared to girls. The aim of this study was to examine the relationship between weight status and HRQoL in 6-7 year olds in this unique country context.
Methods: Baseline HRQoL and demographic data were collected from children recruited to the CHIRPY DRAGON obesity prevention trial in China. HRQoL was measured using the Chinese version of the Child Health Utility-9D (CHU-9D-CHN) and the PedsQL instruments. CHU-9D-CHN utility scores were generated using two scoring algorithms [UK and Chinese tariffs]. Height and weight measures were taken at school by trained researchers using standardised methods, and BMI z-scores were calculated using the WHO 2007 Growth Charts. The relationship between HRQoL and weight status was examined using multivariable analyses, adjusting for age, gender and socio-economic status.
Results: Full data were available for 1,539 children (mean age 6 years). In both unadjusted and adjusted analyses, HRQoL, using both the CHU-9D-CHN and the PedsQL, was marginally higher in children who were overweight/living with obesity compared to children with healthy weight, although this difference did not reach statistical significance. Separate analyses/models by gender, showed that the relationship between weight status and HRQoL scores was similar in boys and girls.
Conclusions: Our results suggest no statistically significant difference in HRQoL between children with overweight/obesity compared to those with healthy weight. These results have implications for the methods of economic evaluation for obesity treatment/prevention interventions within this population cohort and country setting as there appears to be no discernible consequences upon HRQOL from living with overweight/obesity in children.
Methods: Baseline HRQoL and demographic data were collected from children recruited to the CHIRPY DRAGON obesity prevention trial in China. HRQoL was measured using the Chinese version of the Child Health Utility-9D (CHU-9D-CHN) and the PedsQL instruments. CHU-9D-CHN utility scores were generated using two scoring algorithms [UK and Chinese tariffs]. Height and weight measures were taken at school by trained researchers using standardised methods, and BMI z-scores were calculated using the WHO 2007 Growth Charts. The relationship between HRQoL and weight status was examined using multivariable analyses, adjusting for age, gender and socio-economic status.
Results: Full data were available for 1,539 children (mean age 6 years). In both unadjusted and adjusted analyses, HRQoL, using both the CHU-9D-CHN and the PedsQL, was marginally higher in children who were overweight/living with obesity compared to children with healthy weight, although this difference did not reach statistical significance. Separate analyses/models by gender, showed that the relationship between weight status and HRQoL scores was similar in boys and girls.
Conclusions: Our results suggest no statistically significant difference in HRQoL between children with overweight/obesity compared to those with healthy weight. These results have implications for the methods of economic evaluation for obesity treatment/prevention interventions within this population cohort and country setting as there appears to be no discernible consequences upon HRQOL from living with overweight/obesity in children.
| Original language | English |
|---|---|
| Pages (from-to) | 75-81 |
| Number of pages | 7 |
| Journal | Journal of Health Economics and Outcomes Research |
| Volume | 9 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 7 Mar 2022 |
Bibliographical note
Funding Information:Funding: This study was funded through a charitable donation from Zhejiang Yong Ning Pharmaceutical Ltd Co to the University of Birmingham. The analyses were further supported by a University of Birmingham College of Medical and
Publisher Copyright:
© 2022 Columbia Data Analytics. All rights reserved.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Research Groups and Themes
- SPS Exercise, Nutrition and Health Sciences
- SPS Health Social Care and Disability Research Centre
Keywords
- WEIGHT STATUS
- overweight/obesity
- health-related quality of life
- children
- China
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