Reporting of allocation method and statistical analyses that deal with bilaterally affected wrists in clinical trials for carpal tunnel syndrome

Matthew J Page, Denise A O'Connor, Veronica Pitt, Nicola Massy-Westropp

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

Abstract

The authors aimed to describe how often the allocation method and the statistical analyses that deal with bilateral involvement are reported in clinical trials for carpal tunnel syndrome and to determine whether reporting has improved over time. Forty-two trials identified from recently published systematic reviews were assessed. Information about allocation method and statistical analyses was obtained from published reports and trialists. Only 15 trialists (36%) reported the method of random sequence generation used, and 6 trialists (14%) reported the method of allocation concealment used. Of 25 trials including participants with bilateral carpal tunnel syndrome, 17 (68%) reported the method used to allocate the wrists, whereas only 1 (4%) reported using a statistical analysis that appropriately dealt with bilateral involvement. There was no clear trend of improved reporting over time. Interventions are needed to improve reporting quality and statistical analyses of these trials so that these can provide more reliable evidence to inform clinical practice.

Original languageEnglish
Pages (from-to)1012-9
Number of pages8
JournalAmerican Journal of Physical Medicine and Rehabilitation
Volume92
Issue number11
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Carpal Tunnel Syndrome
  • Clinical Trials as Topic
  • Data Interpretation, Statistical
  • Humans
  • Patient Selection
  • Random Allocation

Fingerprint Dive into the research topics of 'Reporting of allocation method and statistical analyses that deal with bilaterally affected wrists in clinical trials for carpal tunnel syndrome'. Together they form a unique fingerprint.

  • Cite this