Response to Comment on "Community-Wide Isoniazid Preventive Therapy Drives Drug-Resistant Tuberculosis: A Model-Based Analysis"

Harriet L. Mills, Ted Cohen*, Caroline Colijn

*Corresponding author for this work

Research output: Contribution to journalLetter (Academic Journal)

20 Citations (Scopus)


Our modeling work suggests that isoniazid preventive therapy (IPT) can be effective in reducing drug-sensitive tuberculosis (TB) and that the risk of IPT driving resistance can be reduced by improving the detection and rapid treatment of individuals with drug-resistant disease and by limiting IPT to those in whom the intervention will have the largest benefit.

Original languageEnglish
Article numberARTN 204lr4
Number of pages2
JournalScience Translational Medicine
Issue number204
Publication statusPublished - 25 Sep 2013



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