Response to Comment on "Community-Wide Isoniazid Preventive Therapy Drives Drug-Resistant Tuberculosis: A Model-Based Analysis"

Harriet L. Mills; Ted Cohen; Caroline Colijn

doi:10.1126/scitranslmed.3007442

Response to Comment on "Community-Wide Isoniazid Preventive Therapy Drives Drug-Resistant Tuberculosis: A Model-Based Analysis"

Harriet L. Mills, Ted Cohen^*, Caroline Colijn

^*Corresponding author for this work

Research output: Contribution to journal › Letter (Academic Journal) › peer-review

23 Citations (Scopus)

Abstract

Our modeling work suggests that isoniazid preventive therapy (IPT) can be effective in reducing drug-sensitive tuberculosis (TB) and that the risk of IPT driving resistance can be reduced by improving the detection and rapid treatment of individuals with drug-resistant disease and by limiting IPT to those in whom the intervention will have the largest benefit.

Original language	English
Article number	ARTN 204lr4
Number of pages	2
Journal	Science Translational Medicine
Volume	5
Issue number	204
DOIs	https://doi.org/10.1126/scitranslmed.3007442
Publication status	Published - 25 Sept 2013

Keywords

PREVALENCE

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1126/scitranslmed.3007442

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abstract = "Our modeling work suggests that isoniazid preventive therapy (IPT) can be effective in reducing drug-sensitive tuberculosis (TB) and that the risk of IPT driving resistance can be reduced by improving the detection and rapid treatment of individuals with drug-resistant disease and by limiting IPT to those in whom the intervention will have the largest benefit.",

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AU - Mills, Harriet L.

AU - Cohen, Ted

AU - Colijn, Caroline

PY - 2013/9/25

Y1 - 2013/9/25

N2 - Our modeling work suggests that isoniazid preventive therapy (IPT) can be effective in reducing drug-sensitive tuberculosis (TB) and that the risk of IPT driving resistance can be reduced by improving the detection and rapid treatment of individuals with drug-resistant disease and by limiting IPT to those in whom the intervention will have the largest benefit.

AB - Our modeling work suggests that isoniazid preventive therapy (IPT) can be effective in reducing drug-sensitive tuberculosis (TB) and that the risk of IPT driving resistance can be reduced by improving the detection and rapid treatment of individuals with drug-resistant disease and by limiting IPT to those in whom the intervention will have the largest benefit.

KW - PREVALENCE

U2 - 10.1126/scitranslmed.3007442

DO - 10.1126/scitranslmed.3007442

M3 - Letter (Academic Journal)

C2 - 24068734

SN - 1946-6234

VL - 5

JO - Science Translational Medicine

JF - Science Translational Medicine

IS - 204

M1 - ARTN 204lr4

ER -

Response to Comment on "Community-Wide Isoniazid Preventive Therapy Drives Drug-Resistant Tuberculosis: A Model-Based Analysis"

Abstract

Keywords

UN SDGs

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