Response to There is little evidence that the endothelial glycocalyx has a specific role in glomerular permeability of albumin

Raina D Ramnath*, Matthew N Butler, R R Foster, Simon C Satchell

*Corresponding author for this work

Research output: Contribution to journalComment/debate (Academic Journal)peer-review

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Abstract

We write in response to the letter entitled “There is little evidence that the endothelial glycocalyx has a specific role in glomerular permeability of albumin,”1 in reference to our original publication.2 The letter title is very misleading. It represents only the opinion of this author and is diametrically opposed to the data presented in our paper and an accumulating body of evidence including in vivo multiphoton measurements.3 This author’s claims are not supported by experimental observations and we and others have addressed them extensively including in a response4 to a previous similar letter. It is curious that the major focus of the letter seems to be on charge selectivity when charge is not mentioned in our paper.
Original languageEnglish
Pages (from-to)1057–1058
Number of pages2
JournalKidney International
Volume97
Issue number5
DOIs
Publication statusPublished - 1 May 2020

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