Resting state predicts neural activity during reward-guided decision making: An fMRI study on Balloon Analogue Risk Task

Claudio Gentili, Elisa Di Rosa*, Ioana Podina, Raluca Popita, Bogdan Voinescu, Daniel David

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

In our previous work [8], we have shown that resting state (RS) functional connectivity metrics are significantly related with behavioural performance at Balloon Analogue Risk Task (BART). In the present study we investigated the hypothesis of an association between RS metrics and neural activity evoked by BART execution. A group-level whole-brain regression was run to assess whether RS metrics predict brain activation during the BART, in a sample of 35 young healthy adults (mean age 23 ± 2 years, 25 F). Results complete the previous findings showing that RS is also significantly associated with the neural activity during BART execution. Specifically, ALFF is positively associated with the activity of both the right inferior parietal lobule and the left caudate. These new results are coherent with previous evidence indicating RS abnormalities in clinical conditions characterised by symptoms of impulse control disorders, and further suggest that RS might be a stable predictor of both behavioural indices and neural correlates of impulsivity and of reward-guided decision-making.

Original languageEnglish
Article number113616
Number of pages3
JournalBehavioural Brain Research
Volume417
Early online date2 Oct 2021
DOIs
Publication statusE-pub ahead of print - 2 Oct 2021

Bibliographical note

Funding Information:
This work was carried out within the scope of the project "use-inspired basic research", for which the Department of General Psychology of the University of Padova has been recognised as "Dipartimento di Eccellenza" by the Ministry of University and Research. EDR was funded by the Marie-Skłodowska-Curie Global Fellowship MOTIVAGEING , GA# 749084 (Horizon 2020).

Publisher Copyright:
© 2021 Elsevier B.V.

Keywords

  • Impulsivity
  • Resting state
  • BARTVBART

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