Abstract
We outline a conceptual blueprint that provides direct and atom economical access to a wide range of complex polyheterocycles. Our method capitalizes on the ambiphilic reactivity of rhodacyclopentanones that arise upon exposure of cyclopropanes to Rh(I) catalysts and CO. Using this approach, a wide array of polycyclizations are achieved, including variants that involve powerful dearomatizations and medium ring formations.
Original language | English |
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Pages (from-to) | 1740-1745 |
Number of pages | 6 |
Journal | Journal of the American Chemical Society |
Volume | 142 |
Issue number | 4 |
Early online date | 21 Jan 2020 |
DOIs | |
Publication status | Published - 29 Jan 2020 |