Risk of first general hospital admissions for self-harm among people with personality disorder: a retrospective cohort study

Kelsey Rush, Marcella Lei Yee Fok, Paul A Moran, Sarah Dorrington, Hitesh Shetty, Robert Stewart, Chin Kuo Chang*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

Abstract

For personality disorder (PD), it is unknown whether additional psychiatric conditions increases their risk of self-harm. We thus performed a retrospective cohort study, using data from secondary mental healthcare in South London, linked to Hospital Episodes Statistics in England to identify self-harm admissions. Adults with diagnosed PD, followed up in a 6-year period, were involved (N=7,475). Cox regression was used to model the risk of self-harm admissions, with comorbid depression, substance use disorders (SUD), severe mental illness (SMI), anorexia nervosa (AN) and bulimia nervosa (BN) as primary exposures, with sociodemographics considered as confounders. In multivariable analyses, comorbid SUD (adjusted HR=1.66; 95%CI: 1.45, 1.90), depressive disorder (1.25; 1.09, 1.44), AN (1.63; 1.10, 2.39) and BN (1.65; 1.09, 2.51) were positively associated with increased risks of hospitalisation due to self-harm. However, negative association was found for comorbid SMI. The findings highlight the importance of assessing and treating comorbid psychiatric disorders in PD.

Original languageEnglish
Number of pages7
JournalJournal of Personality Disorders
Early online date27 Oct 2020
DOIs
Publication statusE-pub ahead of print - 27 Oct 2020

Fingerprint Dive into the research topics of 'Risk of first general hospital admissions for self-harm among people with personality disorder: a retrospective cohort study'. Together they form a unique fingerprint.

Cite this