Risk of stroke from new carotid artery occlusion in the Asymptomatic Carotid Surgery Trial-1

Anne G den Hartog, Alison W Halliday, Elizabeth Hayter, Hongchao Pan, Xing Kong, Frans L Moll, Gert Jan de Borst, Asymptomatic Carotid Surgery Trial Collaborators, Frank C T Smith

Research output: Contribution to journalArticle (Academic Journal)peer-review

17 Citations (Scopus)

Abstract

In the Asymptomatic Carotid Surgery Trial-1 (ACST-1), 3120 patients with tight asymptomatic carotid stenosis were randomly assigned to medical treatment alone or to carotid endarterectomy and appropriate medication. Successful carotid endarterectomy significantly reduced 10-year stroke risk in younger patients. This study was undertaken to determine the risk of new occlusion and stroke during trial follow-up.
Original languageEnglish
Pages (from-to)1652-9
Number of pages8
JournalStroke
Volume44
Issue number6
DOIs
Publication statusPublished - Jun 2013

Keywords

  • Aged
  • Antihypertensive Agents
  • Carotid Stenosis
  • Combined Modality Therapy
  • Endarterectomy, Carotid
  • Female
  • Fibrinolytic Agents
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Proportional Hazards Models
  • Recurrence
  • Risk Factors
  • Stroke
  • Time Factors

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