Robust and effective automatic parameter choice for medical image filtering

Ana João, Alberto Gambaruto, Ricardo Pereira, Adélia Sequeira

Research output: Contribution to journalArticle (Academic Journal)peer-review

6 Citations (Scopus)
151 Downloads (Pure)


The analysis of medical image data currently requires the interpretation of a trained and experienced user. The technological advances in imaging machinery and the understanding of disease onset, as well as medical planning, all favour the need for ever more automatic and robust methods for evaluating the health state of a subject. Here, we concentrate on methods for processing medical image data, as currently provided by existing imaging technologies, in particular the effectiveness of automatic image filtering in order to remove noise and improve the sharpness of distinct objects. The filtering approach is based on a partial differential equation, namely the Perona-Malik anisotropic diffusion equation. The approach adopted for terminating the iterative filtering procedure is based on image quality descriptors. In specific, we observe the rate of change of these to infer the transient effects of the filtering process. The entire pipeline is demonstrated to work effectively on different sets of medical image data, including MRI, CTA and CT, both in individual 2-D images in a stack, as well as treating the complete 3D volumetric dataset.
Original languageEnglish
Pages (from-to)152-168
Number of pages18
JournalComputer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization
Volume8 (2020)
Issue number2
Early online date12 Jul 2019
Publication statusE-pub ahead of print - 12 Jul 2019

Structured keywords

  • Mathematics and Computational Biology


  • Medical imaging processing
  • image quality
  • Perona-Malik filtering
  • automatic algorithm
  • object segmentation


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