Safety and Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 for Spinal Fusion: A Meta-analysis of Individual-Participant Data

Mark C Simmonds, Jennifer V E Brown, Morag K Heirs, Julian P T Higgins, Richard J Mannion, Mark A Rodgers, Lesley A Stewart

Research output: Contribution to journalArticle (Academic Journal)peer-review

224 Citations (Scopus)

Abstract

Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used to promote fusion in spinal surgery, but its safety has been questioned.
Original languageEnglish
Pages (from-to)877-89
Number of pages13
JournalAnnals of Internal Medicine
Volume158
Issue number12
DOIs
Publication statusPublished - 18 Jun 2013

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