Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data

JAP Da Silva; JWG Jacobs; JR Kirwan; M Boers; K Saag; LBS Inês; EJP de Koning; F Buttgereit; M Cutolo; H Capell; R Rau; JWJ Bijlsma

doi:10.1136/ard.2005.038638

Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data

JAP Da Silva
, JWG Jacobs
, JR Kirwan
, M Boers
, K Saag
, LBS Inês
, EJP de Koning
, F Buttgereit
, M Cutolo
, H Capell
, R Rau
, JWJ Bijlsma

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

480 Citations (Scopus)

Abstract

Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence, and impact are supported by clear scientific evidence. Safety data from recent randomised controlled clinical trials of low dose glucocorticoid treatment in RA suggest that adverse effects associated with this drug are modest, and often not statistically different from those of placebo.

Translated title of the contribution	Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data
Original language	English
Pages (from-to)	285 - 293
Number of pages	9
Journal	Annals of the Rheumatic Diseases
Volume	65 (3)
DOIs	https://doi.org/10.1136/ard.2005.038638
Publication status	Published - Mar 2006

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Publisher: BMJ Group

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10.1136/ard.2005.038638

http://ard.bmj.com/cgi/content/abstract/65/3/285

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Da Silva, JAP., Jacobs, JWG., Kirwan, JR., Boers, M., Saag, K., Inês, LBS., de Koning, EJP., Buttgereit, F., Cutolo, M., Capell, H., Rau, R., & Bijlsma, JWJ. (2006). Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Annals of the Rheumatic Diseases, 65 (3), 285 - 293. https://doi.org/10.1136/ard.2005.038638

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abstract = "Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence, and impact are supported by clear scientific evidence. Safety data from recent randomised controlled clinical trials of low dose glucocorticoid treatment in RA suggest that adverse effects associated with this drug are modest, and often not statistically different from those of placebo.",

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year = "2006",

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doi = "10.1136/ard.2005.038638",

language = "English",

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Da Silva, JAP, Jacobs, JWG, Kirwan, JR, Boers, M, Saag, K, Inês, LBS, de Koning, EJP, Buttgereit, F, Cutolo, M, Capell, H, Rau, R & Bijlsma, JWJ 2006, 'Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data', Annals of the Rheumatic Diseases, vol. 65 (3), pp. 285 - 293. https://doi.org/10.1136/ard.2005.038638

TY - JOUR

T1 - Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data

AU - Da Silva, JAP

AU - Jacobs, JWG

AU - Kirwan, JR

AU - Boers, M

AU - Saag, K

AU - Inês, LBS

AU - de Koning, EJP

AU - Buttgereit, F

AU - Cutolo, M

AU - Capell, H

AU - Rau, R

AU - Bijlsma, JWJ

N1 - Publisher: BMJ Group

PY - 2006/3

Y1 - 2006/3

N2 - Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence, and impact are supported by clear scientific evidence. Safety data from recent randomised controlled clinical trials of low dose glucocorticoid treatment in RA suggest that adverse effects associated with this drug are modest, and often not statistically different from those of placebo.

AB - Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence, and impact are supported by clear scientific evidence. Safety data from recent randomised controlled clinical trials of low dose glucocorticoid treatment in RA suggest that adverse effects associated with this drug are modest, and often not statistically different from those of placebo.

U2 - 10.1136/ard.2005.038638

DO - 10.1136/ard.2005.038638

M3 - Article (Academic Journal)

SN - 1468-2060

VL - 65 (3)

SP - 285

EP - 293

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

ER -

Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data

Abstract

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