Salt-induced condensation in actin-DNA mixtures

O. V. Zribi*, H. Kyung, R. Golestanian, T. B. Liverpool, G. C L Wong

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Abstract

Multivalent ions can induce condensation of like-charged polyelectrolytes into compact states, a process that requires different ion valence for different polyelectrolyte species. We have examined the trivalent ion-induced condensation behavior in binary anionic polyelectrolyte mixtures consisting of DNA coils and F-actin rods, and observe a micro-phase separation between the two polyelectrolytes into coexisting finite-sized F-actin bundles and DNA toroids. Further, by increasing the DNA volume fraction in the mixture, condensed F-actin bundles can be completely destabilized, leading to only DNA condensation within the mixture. We examine a number of possible causes and propose a model based on polyelectrolyte competition for ions.

Original languageEnglish
Pages (from-to)541-547
Number of pages7
JournalEPL
Volume70
Issue number4
DOIs
Publication statusPublished - May 2005

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    Zribi, O. V., Kyung, H., Golestanian, R., Liverpool, T. B., & Wong, G. C. L. (2005). Salt-induced condensation in actin-DNA mixtures. EPL, 70(4), 541-547. https://doi.org/10.1209/epl/i2004-10510-1