Scanning the horizon: towards transparent and reproducible neuroimaging research

Russell A. Poldrack*, Chris I. Baker, Joke Durnez, Krzysztof J. Gorgolewski, Paul M Matthews, Marcus R. Munafò, Thomas E. Nichols, Jean Baptiste Poline, Edward Vul, Tal Yarkoni

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

436 Citations (Scopus)
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Functional neuroimaging techniques have transformed our ability to probe the neurobiological basis of behaviour and are increasingly being applied by the wider neuroscience community. However, concerns have recently been raised that the conclusions that are drawn from some human neuroimaging studies are either spurious or not generalizable. Problems such as low statistical power, flexibility in data analysis, software errors and a lack of direct replication apply to many fields, but perhaps particularly to functional MRI. Here, we discuss these problems, outline current and suggested best practices, and describe how we think the field should evolve to produce the most meaningful and reliable answers to neuroscientific questions.

Original languageEnglish
Pages (from-to)115-126
Number of pages12
JournalNature Reviews Neuroscience
Issue number2
Early online date5 Jan 2017
Publication statusPublished - Feb 2017

Structured keywords

  • Brain and Behaviour
  • Tobacco and Alcohol


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