Screening in women's health, with emphasis on fetal Down's syndrome, breast cancer and osteoporosis

Hajo I J Wildschut*, Tim Peters, Carl P. Weiner

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

7 Citations (Scopus)

Abstract

Screening tests have become increasingly popular in women's health care over the last two decades. The initiative for screening is typically generated by either an agency or the health care professional being consulted for some reason. In many instances, however, the demand for screening tests is patient driven with the health care provider being poorly prepared to determine the usefulness of screening. This review illustrates the complexity of screening using three disorders where early detection and treatment have the potential to improve the quality and longevity of life. Prenatal diagnosis of Down's syndrome does not offer the parents the opportunity for cure but does offer the opportunity for education and rational choice as the impact of the diagnosis on the family is weighed. The evidence for breast cancer screening is more persuasive for older than younger women, but even in older women, there is a balance of risks and benefits. Treatment options for osteoporosis have improved in terms of reductions in fracture risk as well as beneficial effects on bone density, but evidence of the effectiveness of a screening programme for this condition in an unselected population is lacking. Ultimately, it is crucial that women be provided with clear and comprehensive information about the screening programme, in terms of possible gains but also costs of various kinds: physical, economic and psychological.

Original languageEnglish
Pages (from-to)499-512
Number of pages14
JournalHuman Reproduction Update
Volume12
Issue number5
Early online date28 Jun 2006
DOIs
Publication statusPublished - Sep 2006

Keywords

  • Breast cancer
  • Down's syndrome
  • Informed choice
  • Osteoporosis
  • Screening

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