Abstract
Although there is general agreement that metformin should be used as first-line pharmacotherapy in patients with type 2 diabetes, uncertainty remains regarding the choice of second-line therapy once metformin is no longer effective. We conducted a systematic review and meta-analysis to assess the comparative safety and efficacy of all available classes of antihyperglycemic therapies in patients with type 2 diabetes inadequately controlled on metformin monotherapy.
| Original language | English |
|---|---|
| Pages (from-to) | e35-48 |
| Journal | Open Medicine |
| Volume | 5 |
| Issue number | 1 |
| Publication status | Published - 2011 |
