SelEXSIDE: Fast and Easy Measurement of Multiple-Bond H-1,C-13 Coupling Constants for Stereochemical Analysis

Craig P. Butts, Bert Heise, Godiraone Tatolo

Research output: Contribution to journalArticle (Academic Journal)peer-review

17 Citations (Scopus)

Abstract

Long-range H-1,C-13 coupling constants ((n)J(CH)) are underutilized parameters for stereochemical structure determination, primarily because they are not easy to measure. This report describes a rapid and easily interpreted method for the measurement of one or more (n)J(CH) values based on a C-13 band-selective EXSIDE (SelEXSIDE), which reduces experiment times from many hours down to a few minutes while allowing a simple and straightforward readout of (n)J(CH) values from the resulting in-phase doublet signal.

Original languageEnglish
Pages (from-to)3256-3259
Number of pages4
JournalOrganic Letters
Volume14
Issue number13
DOIs
Publication statusPublished - 6 Jul 2012

Cite this