Sesquiterpene lactones from Lychnophora ericoides

HT Sakamoto; D Flausino; EE Castellano; CBW Stark; PJ Gates; NP Lopes

doi:10.1021/np020314v

Sesquiterpene lactones from Lychnophora ericoides

HT Sakamoto, D Flausino, EE Castellano, CBW Stark, PJ Gates, NP Lopes^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

50 Citations (Scopus)

Abstract

Two new sesquiterpene lactones, (4S,6R,7S,8S,10R,11S,16R)-1-oxo-3(10),8(16)-diepoxy-16-methylprop-1Z-enyl-16-methoxygermacra-2-en-6(12)-olide (1) and (4S,6R,7S,8S,10R,11S)-1-oxo-3,10-epoxy-8-angeloyloxygermacra-2-en-6(12)-olide (2), were isolated from Lychnophora ericoides. Their structures, including absolute configuration, were established by spectroscopic methods, including single-crystal X-ray analysis. Monitoring the furanoheliangolide metabolism of L. ericoides revealed an increase in biosynthesis during the plant flowering period.

Translated title of the contribution	Sesquiterpene Lactones from Lychnophora ericoides
Original language	English
Pages (from-to)	693-695
Number of pages	3
Journal	Journal of Natural Products
Volume	66
Issue number	5
DOIs	https://doi.org/10.1021/np020314v
Publication status	Published - May 2003

Bibliographical note

Publisher: American Chemical Society

Keywords

NF-KAPPA-B
CONSTITUENTS

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title = "Sesquiterpene lactones from Lychnophora ericoides",

abstract = "Two new sesquiterpene lactones, (4S,6R,7S,8S,10R,11S,16R)-1-oxo-3(10),8(16)-diepoxy-16-methylprop-1Z-enyl-16-methoxygermacra-2-en-6(12)-olide (1) and (4S,6R,7S,8S,10R,11S)-1-oxo-3,10-epoxy-8-angeloyloxygermacra-2-en-6(12)-olide (2), were isolated from Lychnophora ericoides. Their structures, including absolute configuration, were established by spectroscopic methods, including single-crystal X-ray analysis. Monitoring the furanoheliangolide metabolism of L. ericoides revealed an increase in biosynthesis during the plant flowering period.",

keywords = "NF-KAPPA-B, CONSTITUENTS",

author = "HT Sakamoto and D Flausino and EE Castellano and CBW Stark and PJ Gates and NP Lopes",

note = "Publisher: American Chemical Society",

year = "2003",

month = may,

doi = "10.1021/np020314v",

language = "English",

volume = "66",

pages = "693--695",

journal = "Journal of Natural Products",

publisher = "American Chemical Society",

number = "5",

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TY - JOUR

T1 - Sesquiterpene lactones from Lychnophora ericoides

AU - Sakamoto, HT

AU - Flausino, D

AU - Castellano, EE

AU - Stark, CBW

AU - Gates, PJ

AU - Lopes, NP

N1 - Publisher: American Chemical Society

PY - 2003/5

Y1 - 2003/5

N2 - Two new sesquiterpene lactones, (4S,6R,7S,8S,10R,11S,16R)-1-oxo-3(10),8(16)-diepoxy-16-methylprop-1Z-enyl-16-methoxygermacra-2-en-6(12)-olide (1) and (4S,6R,7S,8S,10R,11S)-1-oxo-3,10-epoxy-8-angeloyloxygermacra-2-en-6(12)-olide (2), were isolated from Lychnophora ericoides. Their structures, including absolute configuration, were established by spectroscopic methods, including single-crystal X-ray analysis. Monitoring the furanoheliangolide metabolism of L. ericoides revealed an increase in biosynthesis during the plant flowering period.

AB - Two new sesquiterpene lactones, (4S,6R,7S,8S,10R,11S,16R)-1-oxo-3(10),8(16)-diepoxy-16-methylprop-1Z-enyl-16-methoxygermacra-2-en-6(12)-olide (1) and (4S,6R,7S,8S,10R,11S)-1-oxo-3,10-epoxy-8-angeloyloxygermacra-2-en-6(12)-olide (2), were isolated from Lychnophora ericoides. Their structures, including absolute configuration, were established by spectroscopic methods, including single-crystal X-ray analysis. Monitoring the furanoheliangolide metabolism of L. ericoides revealed an increase in biosynthesis during the plant flowering period.

KW - NF-KAPPA-B

KW - CONSTITUENTS

U2 - 10.1021/np020314v

DO - 10.1021/np020314v

M3 - Article (Academic Journal)

VL - 66

SP - 693

EP - 695

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 5

ER -

Sesquiterpene lactones from Lychnophora ericoides

Abstract

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