Sex differences in alpha-adrenergic support of blood pressure

J A Schmitt; M J Joyner; N Charkoudian; B G Wallin; ECJ Hart

doi:10.1007/s10286-010-0061-y

Sex differences in alpha-adrenergic support of blood pressure

J A Schmitt, M J Joyner, N Charkoudian, B G Wallin, ECJ Hart

School of Physiology, Pharmacology & Neuroscience

Research output: Contribution to journal › Article (Academic Journal) › peer-review

39 Citations (Scopus)

Abstract

We tested whether the inter-individual variability in alpha-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the alpha-adrenergic receptors was achieved via phentolamine and showed a smaller (P <0.05) decrease in blood pressure in women compared to men, implying that alpha-adrenergic support of blood pressure is less in women than in men.

Translated title of the contribution	Sex differences in alpha-adrenergic support of blood pressure
Original language	English
Pages (from-to)	271 - 275
Number of pages	4
Journal	Clinical Autonomic Research
Volume	20
DOIs	https://doi.org/10.1007/s10286-010-0061-y
Publication status	Published - Aug 2010

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title = "Sex differences in alpha-adrenergic support of blood pressure",

abstract = "We tested whether the inter-individual variability in alpha-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the alpha-adrenergic receptors was achieved via phentolamine and showed a smaller (P <0.05) decrease in blood pressure in women compared to men, implying that alpha-adrenergic support of blood pressure is less in women than in men.",

author = "Schmitt, {J A} and Joyner, {M J} and N Charkoudian and Wallin, {B G} and ECJ Hart",

year = "2010",

month = aug,

doi = "10.1007/s10286-010-0061-y",

language = "English",

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TY - JOUR

T1 - Sex differences in alpha-adrenergic support of blood pressure

AU - Schmitt, J A

AU - Joyner, M J

AU - Charkoudian, N

AU - Wallin, B G

AU - Hart, ECJ

PY - 2010/8

Y1 - 2010/8

N2 - We tested whether the inter-individual variability in alpha-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the alpha-adrenergic receptors was achieved via phentolamine and showed a smaller (P <0.05) decrease in blood pressure in women compared to men, implying that alpha-adrenergic support of blood pressure is less in women than in men.

AB - We tested whether the inter-individual variability in alpha-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the alpha-adrenergic receptors was achieved via phentolamine and showed a smaller (P <0.05) decrease in blood pressure in women compared to men, implying that alpha-adrenergic support of blood pressure is less in women than in men.

U2 - 10.1007/s10286-010-0061-y

DO - 10.1007/s10286-010-0061-y

M3 - Article (Academic Journal)

C2 - 20221842

SN - 0959-9851

VL - 20

SP - 271

EP - 275

JO - Clinical Autonomic Research

JF - Clinical Autonomic Research

ER -

Sex differences in alpha-adrenergic support of blood pressure

Abstract

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