Sex differences in the association of apolipoprotein E and Angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: a population-based study from southern Italy

D Seripa, M Franceschi, MG Matera, F Panza, V Solfrizzi, PG Kehoe, C Gravina, G Orsitto, RP D'Andrea, G Di Minno, VM Fazio, B Dallapiccola, A Pilotto

Research output: Contribution to journalArticle (Academic Journal)peer-review

64 Citations (Scopus)

Abstract

We investigated the association of sex and age with the occurrence of apolipoprotein E (apoE) and angiotensin-converting enzyme (ACE) genotypes in healthy aging and longevity in 1344 healthy individuals and 64 centenarians. As compared to participants younger than 60 years, a significant higher frequency of the apoE/epsilon2 was observed in men aged 60-90 years (p
Translated title of the contributionSex differences in the association of apolipoprotein E and Angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: a population-based study from southern Italy
Original languageEnglish
Pages (from-to)918-923
Number of pages6
JournalJournals of Gerontology, Series A
Volume61
Issue number9
Publication statusPublished - Sep 2006

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