Shear-thinning effects of hemodynamics in patient-specific cerebral aneurysms.

Alberto M Gambaruto; Joao Janela; Alexandra Moura; Adélia Sequeira

doi:10.3934/mbe.2013.10.649

Shear-thinning effects of hemodynamics in patient-specific cerebral aneurysms.

Alberto M Gambaruto, Joao Janela, Alexandra Moura, Adélia Sequeira

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Abstract

Two different generalized Newtonian mathematical models for blood flow, derived for the same experimental data, are compared, together with the Newtonian model, in three different anatomically realistic geometries of saccular cerebral aneurysms, obtained from rotational CTA. The geometries differ in size of the aneurysm and the existence or not of side branches within the aneurysm. Results show that the differences between the two generalized Newtonian mathematical models are smaller than the differences between these and the Newtonian solution, in both steady and unsteady simulations.

Original language	English
Pages (from-to)	649-665
Number of pages	17
Journal	Mathematical Biosciences and Engineering
Volume	10
Issue number	3
Early online date	1 Apr 2013
DOIs	https://doi.org/10.3934/mbe.2013.10.649
Publication status	Published - Jun 2013

Keywords

Blood flow modeling
cerebral aneurysm
patient-specific geometry
non-Newtonian blood models

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Gambaruto_et_al_2013-preprint-Shear-thinning effects of hemodynamics in patient-specificcerebral aneurysms
This is the author accepted manuscript (AAM). The final published version (version of record) is available online via AIMS at http://www.aimsciences.org/journals/displayArticlesnew.jsp?paperID=8463. Please refer to any applicable terms of use of the publisher.
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title = "Shear-thinning effects of hemodynamics in patient-specific cerebral aneurysms.",

abstract = "Two different generalized Newtonian mathematical models for blood flow, derived for the same experimental data, are compared, together with the Newtonian model, in three different anatomically realistic geometries of saccular cerebral aneurysms, obtained from rotational CTA. The geometries differ in size of the aneurysm and the existence or not of side branches within the aneurysm. Results show that the differences between the two generalized Newtonian mathematical models are smaller than the differences between these and the Newtonian solution, in both steady and unsteady simulations.",

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author = "Gambaruto, \{Alberto M\} and Joao Janela and Alexandra Moura and Ad{\'e}lia Sequeira",

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AU - Gambaruto, Alberto M

AU - Janela, Joao

AU - Moura, Alexandra

AU - Sequeira, Adélia

PY - 2013/6

Y1 - 2013/6

N2 - Two different generalized Newtonian mathematical models for blood flow, derived for the same experimental data, are compared, together with the Newtonian model, in three different anatomically realistic geometries of saccular cerebral aneurysms, obtained from rotational CTA. The geometries differ in size of the aneurysm and the existence or not of side branches within the aneurysm. Results show that the differences between the two generalized Newtonian mathematical models are smaller than the differences between these and the Newtonian solution, in both steady and unsteady simulations.

AB - Two different generalized Newtonian mathematical models for blood flow, derived for the same experimental data, are compared, together with the Newtonian model, in three different anatomically realistic geometries of saccular cerebral aneurysms, obtained from rotational CTA. The geometries differ in size of the aneurysm and the existence or not of side branches within the aneurysm. Results show that the differences between the two generalized Newtonian mathematical models are smaller than the differences between these and the Newtonian solution, in both steady and unsteady simulations.

KW - Blood flow modeling

KW - cerebral aneurysm

KW - patient-specific geometry

KW - non-Newtonian blood models

U2 - 10.3934/mbe.2013.10.649

DO - 10.3934/mbe.2013.10.649

M3 - Article (Academic Journal)

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EP - 665

JO - Mathematical Biosciences and Engineering

JF - Mathematical Biosciences and Engineering

IS - 3

ER -

Shear-thinning effects of hemodynamics in patient-specific cerebral aneurysms.

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Keywords

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