Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

Wim van der Hoek; Ramu Sarge-Njie; Tineke Herremans; Thomas Chisnall; Joseph Okebe; Eniyou Oriero; Bart Versteeg; Bart Goossens; Marianne van der Sande; Beate Kampmann; Davis Nwakanma

doi:10.1111/tmi.12116

Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

Wim van der Hoek^*, Ramu Sarge-Njie, Tineke Herremans, Thomas Chisnall, Joseph Okebe, Eniyou Oriero, Bart Versteeg, Bart Goossens, Marianne van der Sande, Beate Kampmann, Davis Nwakanma

^*Corresponding author for this work

MRC Integrative Epidemiology Unit

Research output: Contribution to journal › Article (Academic Journal) › peer-review

15 Citations (Scopus)

Abstract

Objective To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. Methods Sera of 796 children aged 1-15years were tested for presence of antibodies against phase II of C.burnetii by ELISA. Results IgG and/or IgM phase II antibodies against C.burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4years. Conclusions Exposure to C.burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

Original language	English
Pages (from-to)	850-853
Number of pages	4
Journal	Tropical Medicine and International Health
Volume	18
Issue number	7
DOIs	https://doi.org/10.1111/tmi.12116
Publication status	Published - Jul 2013

Keywords

Q fever
Coxiella burnetii
seroprevalence
fever
Gambia
SPOTTED-FEVER
SEROPREVALENCE
NETHERLANDS
POPULATION
INFECTION
TANZANIA
TYPHUS

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van der Hoek, W., Sarge-Njie, R., Herremans, T., Chisnall, T., Okebe, J., Oriero, E., Versteeg, B., Goossens, B., van der Sande, M., Kampmann, B., & Nwakanma, D. (2013). Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa. Tropical Medicine and International Health, 18(7), 850-853. https://doi.org/10.1111/tmi.12116

van der Hoek, Wim ; Sarge-Njie, Ramu ; Herremans, Tineke et al. / Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa : Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa. In: Tropical Medicine and International Health. 2013 ; Vol. 18, No. 7. pp. 850-853.

@article{a797a9351aa541f899d7ac9c114fb631,

title = "Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa",

abstract = "Objective To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. Methods Sera of 796 children aged 1-15years were tested for presence of antibodies against phase II of C.burnetii by ELISA. Results IgG and/or IgM phase II antibodies against C.burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4years. Conclusions Exposure to C.burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.",

keywords = "Q fever, Coxiella burnetii, seroprevalence, fever, Gambia, SPOTTED-FEVER, SEROPREVALENCE, NETHERLANDS, POPULATION, INFECTION, TANZANIA, TYPHUS",

author = "{van der Hoek}, Wim and Ramu Sarge-Njie and Tineke Herremans and Thomas Chisnall and Joseph Okebe and Eniyou Oriero and Bart Versteeg and Bart Goossens and {van der Sande}, Marianne and Beate Kampmann and Davis Nwakanma",

year = "2013",

month = jul,

doi = "10.1111/tmi.12116",

language = "English",

volume = "18",

pages = "850--853",

journal = "Tropical Medicine and International Health",

issn = "1360-2276",

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van der Hoek, W, Sarge-Njie, R, Herremans, T, Chisnall, T, Okebe, J, Oriero, E, Versteeg, B, Goossens, B, van der Sande, M, Kampmann, B & Nwakanma, D 2013, 'Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa', Tropical Medicine and International Health, vol. 18, no. 7, pp. 850-853. https://doi.org/10.1111/tmi.12116

Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa : Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa. / van der Hoek, Wim; Sarge-Njie, Ramu; Herremans, Tineke et al.

In: Tropical Medicine and International Health, Vol. 18, No. 7, 07.2013, p. 850-853.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

T2 - Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

AU - van der Hoek, Wim

AU - Sarge-Njie, Ramu

AU - Herremans, Tineke

AU - Chisnall, Thomas

AU - Okebe, Joseph

AU - Oriero, Eniyou

AU - Versteeg, Bart

AU - Goossens, Bart

AU - van der Sande, Marianne

AU - Kampmann, Beate

AU - Nwakanma, Davis

PY - 2013/7

Y1 - 2013/7

N2 - Objective To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. Methods Sera of 796 children aged 1-15years were tested for presence of antibodies against phase II of C.burnetii by ELISA. Results IgG and/or IgM phase II antibodies against C.burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4years. Conclusions Exposure to C.burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

AB - Objective To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. Methods Sera of 796 children aged 1-15years were tested for presence of antibodies against phase II of C.burnetii by ELISA. Results IgG and/or IgM phase II antibodies against C.burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4years. Conclusions Exposure to C.burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

KW - Q fever

KW - Coxiella burnetii

KW - seroprevalence

KW - fever

KW - Gambia

KW - SPOTTED-FEVER

KW - SEROPREVALENCE

KW - NETHERLANDS

KW - POPULATION

KW - INFECTION

KW - TANZANIA

KW - TYPHUS

U2 - 10.1111/tmi.12116

DO - 10.1111/tmi.12116

M3 - Article (Academic Journal)

C2 - 23600611

VL - 18

SP - 850

EP - 853

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

SN - 1360-2276

IS - 7

ER -

van der Hoek W, Sarge-Njie R, Herremans T, Chisnall T, Okebe J, Oriero E et al. Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa. Tropical Medicine and International Health. 2013 Jul;18(7):850-853. doi: 10.1111/tmi.12116