Short Communication: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa: Prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

Wim van der Hoek*, Ramu Sarge-Njie, Tineke Herremans, Thomas Chisnall, Joseph Okebe, Eniyou Oriero, Bart Versteeg, Bart Goossens, Marianne van der Sande, Beate Kampmann, Davis Nwakanma

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Abstract

Objective To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. Methods Sera of 796 children aged 1-15years were tested for presence of antibodies against phase II of C.burnetii by ELISA. Results IgG and/or IgM phase II antibodies against C.burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4years. Conclusions Exposure to C.burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

Original languageEnglish
Pages (from-to)850-853
Number of pages4
JournalTropical Medicine and International Health
Volume18
Issue number7
DOIs
Publication statusPublished - Jul 2013

Keywords

  • Q fever
  • Coxiella burnetii
  • seroprevalence
  • fever
  • Gambia
  • SPOTTED-FEVER
  • SEROPREVALENCE
  • NETHERLANDS
  • POPULATION
  • INFECTION
  • TANZANIA
  • TYPHUS

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