Abstract
Parathyroid hormone analog PTH(1–34), used clinically to treat osteoporosis, forms a stable complex with its receptor and prolongs cAMP production even after internalization and recruitment to endosomes. New data suggest this signaling cascade is stimulated by β-arrestins and terminated by retromer
| Translated title of the contribution | Signaling: retromer arrests receptor on the run |
|---|---|
| Original language | English |
| Pages (from-to) | 251 - 252 |
| Number of pages | 2 |
| Journal | Nature Chemical Biology |
| Volume | 7 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2011 |