Silence is golden, but my measures still see—why cheaper-but-noisier outcome measures in large simple trials can be more cost-effective than gold standards

Benjamin Woolf; Hugo Pedder; Henry Rodriguez-Broadbent; Phil Edwards

doi:10.1186/s13063-024-08374-5

Silence is golden, but my measures still see—why cheaper-but-noisier outcome measures in large simple trials can be more cost-effective than gold standards

Benjamin Woolf^*, Hugo Pedder, Henry Rodriguez-Broadbent, Phil Edwards

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Abstract

BW is funded by an Economic and Social Research Council (ESRC) South West Doctoral Training Partnership (SWDTP) 1 + 3 PhD Studentship Award (ES/P000630/1) and the Wellcome Trust (225790/Z/22/Z). CJR is supported by BHF Senior Basic Science Research fellowship FS/SBSRF/21/31025. The research was supported by the United Kingdom Research and Innovation Medical Research Council (MC_UU_000011/7 and MC_UU_00002/7). For the purpose of open access, the authors have applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising.

Original language	English
Article number	532
Journal	Trials
Volume	25
Issue number	1
DOIs	https://doi.org/10.1186/s13063-024-08374-5
Publication status	Published - 12 Aug 2024

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© The Author(s) 2024.

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title = "Silence is golden, but my measures still see—why cheaper-but-noisier outcome measures in large simple trials can be more cost-effective than gold standards",

abstract = "BW is funded by an Economic and Social Research Council (ESRC) South West Doctoral Training Partnership (SWDTP) 1 + 3 PhD Studentship Award (ES/P000630/1) and the Wellcome Trust (225790/Z/22/Z). CJR is supported by BHF Senior Basic Science Research fellowship FS/SBSRF/21/31025. The research was supported by the United Kingdom Research and Innovation Medical Research Council (MC_UU_000011/7 and MC_UU_00002/7). For the purpose of open access, the authors have applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising.",

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AU - Woolf, Benjamin

AU - Pedder, Hugo

AU - Rodriguez-Broadbent, Henry

AU - Edwards, Phil

PY - 2024/8/12

Y1 - 2024/8/12

N2 - BW is funded by an Economic and Social Research Council (ESRC) South West Doctoral Training Partnership (SWDTP) 1 + 3 PhD Studentship Award (ES/P000630/1) and the Wellcome Trust (225790/Z/22/Z). CJR is supported by BHF Senior Basic Science Research fellowship FS/SBSRF/21/31025. The research was supported by the United Kingdom Research and Innovation Medical Research Council (MC_UU_000011/7 and MC_UU_00002/7). For the purpose of open access, the authors have applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising.

AB - BW is funded by an Economic and Social Research Council (ESRC) South West Doctoral Training Partnership (SWDTP) 1 + 3 PhD Studentship Award (ES/P000630/1) and the Wellcome Trust (225790/Z/22/Z). CJR is supported by BHF Senior Basic Science Research fellowship FS/SBSRF/21/31025. The research was supported by the United Kingdom Research and Innovation Medical Research Council (MC_UU_000011/7 and MC_UU_00002/7). For the purpose of open access, the authors have applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising.

U2 - 10.1186/s13063-024-08374-5

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M3 - Article (Academic Journal)

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JO - Trials

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IS - 1

M1 - 532

ER -

Silence is golden, but my measures still see—why cheaper-but-noisier outcome measures in large simple trials can be more cost-effective than gold standards

Abstract

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