SimMLST: simulation of multi-locus sequence typing data under a neutral model

Xavier Didelot; Daniel Lawson; Daniel Falush

doi:10.1093/bioinformatics/btp145

SimMLST: simulation of multi-locus sequence typing data under a neutral model

Xavier Didelot^*, Daniel Lawson, Daniel Falush

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

12 Citations (Scopus)

Abstract

Multi-locus sequence typing (MLST) is a widely used method of characterization of bacterial isolates. It has been applied to over 50 000 isolates in over 50 different species. Here, we present a coalescent method to jointly simulate MLST data and the clonal genealogy that gave rise to the sample.

Original language	English
Pages (from-to)	1442-1444
Number of pages	3
Journal	Bioinformatics
Volume	25
Issue number	11
DOIs	https://doi.org/10.1093/bioinformatics/btp145
Publication status	Published - 1 Jun 2009

Keywords

NEISSERIA-MENINGITIDIS
CAMPYLOBACTER-JEJUNI
MONTE-CARLO
RECOMBINATION
EVOLUTION
POPULATIONS
SELECTION
MUTATION

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10.1093/bioinformatics/btp145

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title = "SimMLST: simulation of multi-locus sequence typing data under a neutral model",

abstract = "Multi-locus sequence typing (MLST) is a widely used method of characterization of bacterial isolates. It has been applied to over 50 000 isolates in over 50 different species. Here, we present a coalescent method to jointly simulate MLST data and the clonal genealogy that gave rise to the sample.",

keywords = "NEISSERIA-MENINGITIDIS, CAMPYLOBACTER-JEJUNI, MONTE-CARLO, RECOMBINATION, EVOLUTION, POPULATIONS, SELECTION, MUTATION",

author = "Xavier Didelot and Daniel Lawson and Daniel Falush",

year = "2009",

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doi = "10.1093/bioinformatics/btp145",

language = "English",

volume = "25",

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TY - JOUR

T1 - SimMLST

T2 - simulation of multi-locus sequence typing data under a neutral model

AU - Didelot, Xavier

AU - Lawson, Daniel

AU - Falush, Daniel

PY - 2009/6/1

Y1 - 2009/6/1

N2 - Multi-locus sequence typing (MLST) is a widely used method of characterization of bacterial isolates. It has been applied to over 50 000 isolates in over 50 different species. Here, we present a coalescent method to jointly simulate MLST data and the clonal genealogy that gave rise to the sample.

AB - Multi-locus sequence typing (MLST) is a widely used method of characterization of bacterial isolates. It has been applied to over 50 000 isolates in over 50 different species. Here, we present a coalescent method to jointly simulate MLST data and the clonal genealogy that gave rise to the sample.

KW - NEISSERIA-MENINGITIDIS

KW - CAMPYLOBACTER-JEJUNI

KW - MONTE-CARLO

KW - RECOMBINATION

KW - EVOLUTION

KW - POPULATIONS

KW - SELECTION

KW - MUTATION

U2 - 10.1093/bioinformatics/btp145

DO - 10.1093/bioinformatics/btp145

M3 - Article (Academic Journal)

C2 - 19286834

VL - 25

SP - 1442

EP - 1444

JO - Bioinformatics

JF - Bioinformatics

SN - 1367-4803

IS - 11

ER -

SimMLST: simulation of multi-locus sequence typing data under a neutral model

Abstract

Keywords

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