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Simplicity, Flexibility, and Interpretability in a Model of Dendritic Protein Distributions

Research output: Contribution to journalShort survey

Original languageEnglish
Pages (from-to)950-952
Number of pages3
JournalNeuron
Volume103
Issue number6
DOIs
DateAccepted/In press - 1 Sep 2019
DatePublished (current) - 25 Sep 2019

Abstract

In this issue of Neuron, Fonkeu et al. (2019) present a mathematical model of mRNA and protein synthesis, degradation, diffusion, and trafficking in neuronal dendrites. The model can predict the spatial distribution and temporal dynamics of proteins along dendrites. The authors use the model to account for in situ imaging data of CaMKII⍺ mRNA and protein in hippocampal neurons.

Additional information

The acceptance date for this record is provisional and based upon the month of publication for the article.

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