Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis

Manuela Savino*, Anna Casula, Shalini Santhakumaran, David Pitcher, Esther Wong, Winnie Magadi, Katharine Evans, Fran Benoy-Deeney, James Griffin, Lucy Plumb, Retha Steenkamp, Dorothea Nitsch, James Medcalf

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

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Abstract

Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1–88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94–1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group.
Original languageEnglish
Article numberE0241263
Number of pages8
JournalPLoS ONE
Volume15
Issue number10
Publication statusPublished - 23 Oct 2020

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