Somatomedin-binding proteins: what role do they play in the growth process?

S Cianfarani, J M Holly

Research output: Contribution to journalArticle (Academic Journal)peer-review

18 Citations (Scopus)


The insulin-like growth factors (IGF-I and IGF-II) circulate bound to specific proteins. Two classes of binding proteins have been relatively well characterized differing in size, immunological activity, and physiological function. This review summarizes the more recent data on IGF-binding proteins, focusing on their possible clinical implications.
Original languageEnglish
Pages (from-to)76-9
Number of pages4
JournalEuropean Journal of Pediatrics
Issue number2
Publication statusPublished - 1989


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