Somatostatin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database.

Corinne Bosquet, Justano Castaño, Zsolt Csaba, Micheal Culler, Pascal Dournaud, Jacques Epelbaum, Wasyl Feniuk, Anthony Harmar, Rebecca Hills, Leo Hofland, Daniel Hoyer, Patrick Humphrey, Hans-Jürgen Kreienkamp, Amelie Lupp, Shlomo Melmed, Wolfgang Meyerhof, Anne-Marie O'Carroll, Yogesh Patel, Terry Reisine, Jean-Claude ReubiMarcus Schindler, Herbert Schmid, Agnes Schonbrunn, Stefan Schulz, John Taylor, Giovanni Tulipano, Annamaria Vezzani, Hans-Jürgen Wester

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Somatostatin (somatotropin release inhibiting factor) is an abundant neuropeptide, which acts on five subtypes of somatostatin receptor (SST1-SST5; nomenclature as agreed by the NC-IUPHAR Subcommittee on Somatostatin Receptors [89]). Activation of these receptors produces a wide range of physiological effects throughout the body including the inhibition of secretion of many hormones. Endogenous ligands for these receptors are somatostatin-14 (SRIF-14) and somatostatin-28 (SRIF-28). cortistatin-14 has also been suggested to be an endogenous ligand for somatostatin receptors
Original languageEnglish
Number of pages17
JournalIUPHAR/BPS Guide to PHarmacology CITE
Publication statusPublished - 16 Sep 2019


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