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Spontaneous membrane-less multi-compartmentalisation via aqueous two-phase separation in complex coacervate microdroplets

  • Nicolette G Moreau
  • , Nicolas C Martin
  • , Pierangelo Gobbo
  • , T D Tang
  • , Stephen Mann*
    • *Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

50 Citations (Scopus)
103 Downloads (Pure)

Abstract

Polyelectrolyte/nucleotide multiphase complex coacervate droplets are produced by internalized aqueous two-phase separation and used for the spatially dependent chemical transfer of sugar molecules, providing a step towards the development of membrane-free “organelles” within coacervate-based protocells.
Original languageEnglish
Pages (from-to)12717-12720
Number of pages5
JournalChem. Commun.
Volume56
Early online date10 Sept 2020
DOIs
Publication statusPublished - 28 Oct 2020

Research Groups and Themes

  • BrisSynBio
  • Bristol BioDesign Institute
  • Max Planck Bristol
  • Inorganic & Materials

Keywords

  • synthetic biology

Access to Document

  • Full-text PDF (final published version)

    This is the final published version of the article (version of record). It first appeared online via Royal Society of Chemistry at https://doi.org/10.1039/d0cc05399f . Please refer to any applicable terms of use of the publisher.

    Final published version, 2.92 MBLicence: CC BY

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