Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer-nucleotide coacervate droplets

John Crosby*, Tom Treadwell, Michelle Hammerton, Konstantinos Vasilakis, Matthew P Crump, David S Williams, Stephen Mann

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

57 Citations (Scopus)

Abstract

Compartmentalization of the minimal complex of actinorhodin polyketide synthase in coacervate liquid droplets produces enhanced yields of shunt polyketides under conditions of low and high ionic strength.

Original languageEnglish
Pages (from-to)11832-11834
Number of pages3
JournalChemical Communications
Volume48
Issue number97
DOIs
Publication statusPublished - 2012

Keywords

  • ACYL CARRIER PROTEIN
  • AROMATIC POLYKETIDES
  • BIOSYNTHESIS

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