Standards for the development and methodology of the 2019 International Working Group on the Diabetic Foot guidelines

Sicco A Bus*, Jaap J van Netten, Robert J Hinchliffe, Jan Apelqvist, Benjamin A Lipsky, Nicolaas C Schaper, IWGDF Editorial Board

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

16 Downloads (Pure)


Diabetic foot disease is a source of major patient suffering and societal costs. Investing in evidence-based international guidelines on diabetic foot disease is likely among the most cost-effective forms of healthcare expenditure, provided the guidelines are outcome-focused, evidence-based and properly implemented.

The International Working Group on the Diabetic Foot (IWGDF) has published and updated international guidelines since 1999. The 2019 updates are based on formulating relevant clinical questions and outcomes, rigorous systematic reviews of the literature, and recommendations that are specific, and unambiguous along with their transparent rationale, all using the Grading of Recommendations Assessment Development and Evaluation (GRADE) framework.

We herein describe the development of the 2019 IWGDF Guidelines on the prevention and management of diabetic foot disease, which consists of six chapters, each prepared by a separate working group of international experts. These documents provide guidelines related to diabetic foot disease on: prevention; offloading; peripheral artery disease; infection; wound healing interventions; and, classification of diabetic foot ulcers. Based on these six chapters, the IWGDF Editorial Board also produced a set of practical guidelines. Each guideline underwent extensive review by the members of the IWGDF Editorial Board as well as independent international experts in each field.

We believe that adoption and implementation of the 2019 IWGDF guidelines by healthcare providers, public health agencies, and policy makers has the potential to improve prevention and management of diabetic foot disease, and to subsequently reduce the worldwide patient and societal burden this disease causes.
Original languageEnglish
Article numbere3267
Number of pages7
JournalDiabetes/Metabolism Research and Reviews
Issue numberS1
Early online date9 Jan 2020
Publication statusPublished - 16 Mar 2020


  • diabetic foot
  • foot ulcer
  • guidance
  • guidelines
  • daily practice
  • implementation
  • education
  • footwear
  • offloading
  • peripheral artery disease
  • infection
  • interdisciplinary treatment


Dive into the research topics of 'Standards for the development and methodology of the 2019 International Working Group on the Diabetic Foot guidelines'. Together they form a unique fingerprint.

Cite this