A study of the statistical mechanics of double-helical polymers using analytical techniques and simulations was presented. A geometric model, which includes three important ingredients of DNA in B-form was introduced. The bending and twisting rigidity of the polymer were determined by single energy scale of the model. It was observed that the helix melts at a particular temperature Tc below which the chain has a helical structure. It was suggested that as in mechanical unzipping experiments on DNA, there could be cooperative effects due to the effects of sequence disorder.
|Journal||Physical Review E: Statistical, Nonlinear, and Soft Matter Physics|
|Issue number||6 1|
|Publication status||Published - Jun 2004|