Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

Hennie Valkenier; Christopher M. Dias; Kathryn L. Porter Goff; Ondřej Jurček; Rakesh Puttreddy; Kari Rissanen; Anthony P. Davis

doi:10.1039/c5cc05737j

Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

Hennie Valkenier^*, Christopher M. Dias, Kathryn L. Porter Goff, Ondřej Jurček, Rakesh Puttreddy, Kari Rissanen, Anthony P. Davis

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

22 Citations (Scopus)

Abstract

Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.

Original language	English
Pages (from-to)	14235-14238
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	75
DOIs	https://doi.org/10.1039/c5cc05737j
Publication status	Published - 30 Jul 2015

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BCS and TECS CDTs

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10.1039/c5cc05737j

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3 Finished

3-month Core Capability for Chemistry Research
Crosby, J.
1/01/13 → 1/04/13
Project: Research
Synthetic Anionophores with Therapeutic Potential - a Coordinated Two-Centre Approach
Davis, A. P.
10/09/12 → 9/03/16
Project: Research
SYNTHETIC ANION CARRIERS FOR BIOMEDICAL APPLICATIONS
Davis, A. P.
1/11/08 → 1/03/12
Project: Research

Cite this

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title = "Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility",

abstract = "Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.",

author = "Hennie Valkenier and Dias, {Christopher M.} and {Porter Goff}, {Kathryn L.} and Ond{\v r}ej Jur{\v c}ek and Rakesh Puttreddy and Kari Rissanen and Davis, {Anthony P.}",

year = "2015",

month = jul,

day = "30",

doi = "10.1039/c5cc05737j",

language = "English",

volume = "51",

pages = "14235--14238",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "75",

}

Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility. / Valkenier, Hennie; Dias, Christopher M.; Porter Goff, Kathryn L.; Jurček, Ondřej; Puttreddy, Rakesh; Rissanen, Kari; Davis, Anthony P.

In: Chemical Communications, Vol. 51, No. 75, 30.07.2015, p. 14235-14238.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

AU - Valkenier, Hennie

AU - Dias, Christopher M.

AU - Porter Goff, Kathryn L.

AU - Jurček, Ondřej

AU - Puttreddy, Rakesh

AU - Rissanen, Kari

AU - Davis, Anthony P.

PY - 2015/7/30

Y1 - 2015/7/30

N2 - Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.

AB - Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.

UR - http://www.scopus.com/inward/record.url?scp=84940989245&partnerID=8YFLogxK

U2 - 10.1039/c5cc05737j

DO - 10.1039/c5cc05737j

M3 - Article (Academic Journal)

C2 - 26260730

AN - SCOPUS:84940989245

VL - 51

SP - 14235

EP - 14238

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 75

ER -

Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

Abstract

Structured keywords

Access to Document

3-month Core Capability for Chemistry Research

Synthetic Anionophores with Therapeutic Potential - a Coordinated Two-Centre Approach

SYNTHETIC ANION CARRIERS FOR BIOMEDICAL APPLICATIONS

Cite this